ELEVATION OF SERUM C-REACTIVE PROTEIN AS A PREDICTOR FOR SYSTEMIC INFLAMMATORY RESPONSE SYNDROME IN CERVICAL SPINAL CORD INJURY PATIENTS

摘要

Objectives: Spinal cord injury has been an important medical issue with high incidence,?complications, and mortality rate. For the past 2 decades, there have been a number of researches?about the role of inflammatory mediators in trauma patients. However, up to now, there were limitedreferences about the role of CRP as a predictor of SIRS in cervical spinal cord injury. Methods: This?was an analytical prospective cohort study of 28 patients to determine the role of increase CRP serumas a predictor for SIRS in cervical spinal cord injury in Sanglah General Hospital, Bali-Indonesia. The?data were descriptively analyzed by applying univariate and multivariate analysis to determine the?role of increase CRP serum with SIRS in cervical spinal cord injury. Results were considered?significant if p < 0.05. Results: From 28 samples collected, 18 samples (64.28%) were male, 12?samples were in >50 years old age group (42,86%), and the most frequent spinal cord injury scale was?ASIA A (12 samples, 42,86%). Both univariate and multivariate analysis showed that increased serumCRP and ASIA Score were significant predictors of SIRS in cervical spinal cord injury patients. Conclusion: Increase in serum CRP value can be used as a reliable predictor for SIRS in cervicalspinal cord injury patients.