Numerical analysis of electromagnetic interactions by a cell during the mitosis phases

摘要

In this work, a numerical study of the interaction of an electromagnetic field with a biological cell in the different phases of mitosis is presented. In particular, the validity of the single-shell model during mitosis from a geometrical viewpoint has been considered. We consider the Jurkat cell for our analysis and model the content of the cell, composed by the nucleus and different organelles immersed in cytoplasm and delimited by the cell membrane, as a single material with appropriate electromagnetic properties derived by making use of effective medium approximation methods, i.e., we used a quasistatic approach to deal with the cell. To validate the model, a comparison between the original and 2 approximated geometry models is made and the results are in very good accordance. Subsequently, an analysis of the scattered field indicates that the most sensitive component to the mitosis phase is the one parallel to the segment joining the centers of the cells.