Quantitative iTRAQ-Based Proteomic Identification of Candidate Biomarkers for Diabetic Nephropathy in Plasma of Type 1 Diabetic Patients

Anne Julie Overgaard; Tine E. Thingholm; Martin R. Larsen; Lise Tarnow; Peter Rossing; James N. McGuire; Flemming Pociot

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Quantitative iTRAQ-Based Proteomic Identification of Candidate Biomarkers for Diabetic Nephropathy in Plasma of Type 1 Diabetic Patients

机译：基于定量iTRAQ的蛋白质组学鉴定，用于1型糖尿病患者血浆中糖尿病肾病的候选生物标志物

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摘要

As part of a clinical proteomics programme focused on diabetes and its complications, it was our goal to investigate the proteome of plasma in order to find improved candidate biomarkers to predict diabetic nephropathy.

机译：作为专注于糖尿病及其并发症的临床蛋白质组学计划的一部分，我们的目标是研究血浆蛋白质组，以发现改良的候选生物标志物来预测糖尿病性肾病。

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《Clinical Proteomics》 |2010年第4期|p.105-114|共10页
作者
Anne Julie Overgaard; Tine E. Thingholm; Martin R. Larsen; Lise Tarnow; Peter Rossing; James N. McGuire; Flemming Pociot;
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作者单位

Hagedorn Research Institute, Novo Nordisk A/S, Niels Steensens Vej 1, 2820, Gentofte, Denmark;

Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, 5230, Odense, Denmark;

Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, 5230, Odense, Denmark;

Steno Diabetes Center, Niels Steensens Vej 1, 2820, Gentofte, Denmark;

Steno Diabetes Center, Niels Steensens Vej 1, 2820, Gentofte, Denmark;

Hagedorn Research Institute, Novo Nordisk A/S, Niels Steensens Vej 1, 2820, Gentofte, Denmark;

Hagedorn Research Institute, Novo Nordisk A/S, Niels Steensens Vej 1, 2820, Gentofte, Denmark;

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正文语种 eng
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关键词
Quantitative proteomics; Diabetic nephropathy; iTRAQ; Protein networks; Pathway analysis; Multiplex immunoassay technology;

机译：定量蛋白质组学;糖尿病肾病;iTRAQ;蛋白质网络;途径分析;多重免疫测定技术;

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1. Quantitative iTRAQ-Based Proteomic Identification of Candidate Biomarkers for Diabetic Nephropathy in Plasma of Type 1 Diabetic Patients [J] . Anne Julie Overgaard, Tine E. Thingholm, Martin R. Larsen, Clinical proteomics. . 2010,第4期

机译：基于定量iTRAQ的蛋白质组学鉴定，用于1型糖尿病患者血浆中糖尿病肾病的候选生物标志物
2. Quantitative iTRAQ-Based Proteomic Identification of Candidate Biomarkers for Diabetic Nephropathy in Plasma of Type 1 Diabetic Patients [J] . Anne Julie Overgaard, Tine E. Thingholm, Martin R. Larsen, Clinical proteomics. . 2010,第4期

机译：基于定量iTRAQ的蛋白质组学鉴定，用于1型糖尿病患者血浆中糖尿病肾病的候选生物标志物
3. Quantitative iTRAQ-Based Proteomic Identification of Candidate Biomarkers for Diabetic Nephropathy in Plasma of Type 1 Diabetic Patients [J] . Anne Julie Overgaard, Tine E. Thingholm, Martin R. Larsen, Clinical proteomics. . 2010,第4期

机译：基于ITRAQ型糖尿病患者血浆糖尿病肾病患者候选生物标志物的蛋白质组学鉴定
4. Proteomic identification of biomarkers of early diabetic nephropathy (dn): pilot study [C] . del Bosque-Plata L., Gutierrez-Nájera N., Adame-García SR. International Congress on Nutrition and Metabolism in Renal Disease . 2010

机译：早期糖尿病肾病的蛋白质组学鉴定（DN）：试验研究
5. Genetic and physiologic characterization of diabetic nephropathy in the type II diabetic nephropathy (T2DN) rat [D] . Schlick, Nancy Elizabeth 2006

机译：II型糖尿病肾病（T2DN）大鼠的糖尿病肾病的遗传和生理学表征
6. Quantitative iTRAQ-Based Proteomic Identification of Candidate Biomarkers for Diabetic Nephropathy in Plasma of Type 1 Diabetic Patients [O] . Anne Julie Overgaard, Tine E. Thingholm, Martin R. Larsen, -1

机译：基于定量iTRAQ的蛋白质组学鉴定用于1型糖尿病患者血浆中糖尿病肾病的候选生物标志物
7. Quantitative iTRAQ-Based Proteomic Identification of Candidate Biomarkers for Diabetic Nephropathy in Plasma of Type 1 Diabetic Patients [O] . Anne Julie Overgaard, Tine E. Thingholm, Martin R. Larsen, 2010

机译：基于定量iTRAQ的蛋白质组学鉴定，用于1型糖尿病患者血浆中糖尿病肾病的候选生物标志物

Quantitative iTRAQ-Based Proteomic Identification of Candidate Biomarkers for Diabetic Nephropathy in Plasma of Type 1 Diabetic Patients

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