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首页> 外文期刊>Chinese Medical Journal >Comparison of three doses of enalapril in preventing left ventricular remodeling after acute myocardial infarction in the rat
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Comparison of three doses of enalapril in preventing left ventricular remodeling after acute myocardial infarction in the rat

机译:三种剂量的依那普利预防大鼠急性心肌梗死后左心室重构的比较

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摘要

Conclusions High, middle and low doses of enalapril were all effective in preventing LVRM after AMI in the rat, with low dose enalapril being effective and high dose superior. As for LV functional improvement, only high and middle-dose enalapril were effective. Objective To compare the effects of high, middle and low doses of enalapril in preventing left ventricular Remodeling(LVRM)after acute myocardial infarction(AMI)in rats, especially evaluating the efficacy of low Dose enalapril. Methods AMI was induced by ligating the left coronary artery in 149 female SD rats.
机译:结论高,中,低剂量的依那普利均能有效预防AMI后LVRM,其中低剂量的依那普利有效,高剂量的依那普利更有效。至于左室功能改善,只有大剂量和中剂量的依那普利有效。目的比较高,中,低剂量依那普利预防急性心肌梗死(AMI)大鼠左心室重构(LVRM)的作用,尤其是评估低剂量依那普利的疗效。方法结扎149只SD大鼠的左冠状动脉引起AMI。

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