METHOD FOR PREDICTING TYPE OF EARLY LEFT VENTRICULAR REMODELING IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION

摘要

FIELD: medicine.;SUBSTANCE: invention relates to the field of medicine, in particular, to cardiology, and is intended to predict the type of early left ventricular remodelling (LVR) in patients with acute myocardial infarction. On the first day the concentration of CITP in the serum is determined, the polymorphism of the MMP20 rs2245803 and COL1A1 rs1107946 genes are investigated and the prognostic coefficient p(LVR) is calculated. When the values of the prognostic coefficient p (LVR)0.34 predict the development of hypertrophic type of early left ventricular remodelling. When the coefficient p(RL)0.34 predict dilatation type changes in the geometry of the left ventricle.;EFFECT: invention allows for an integrated approach in the examination of patients in the early period of myocardial infarction, singling out among them a group of patients with a high risk of developing an adverse type of left ventricular geometry, predisposing to a more severe course of heart failure.;1 cl, 1 dwg, 2 ex, 1 tbl