Effect of Bushen Huoxue Tablet on Serum Lipid Peroxide Blood Lipid and Blood Sugar in Type Ⅱ Diabetics

摘要

Sixty-eight patients suffering from diabetes mellitus (DM) type Ⅱ with Kidney Deficiency and blood stasis Syndrome were enrolled and divided randomly into treatment group (34 cases) and placebo group (34 cases). The contents of serum lipid peroxide (LPO), blood lipid and blood sugar were determined. The results showed that the serum LPO in treatment group was higher than that in placebo group (P < 0.05), it increased significantly in DM patients with vascular disease or with uncontrolled blood sugar and was positively correlated with level of triglyceride (TG, r = 0.25, P < 0.05). After using Bushen Huoxue tablet (BSHXT) serum LPO lowered (P < 0.05), blood sugar decreased (P < 0.05) and high density lipopro-tein-cholesterol (HDL-C) increased (P < 0.05) in treatment group, but in placebo group these three parameters were not changed significantly. These results indicated that LPO reaction in type Ⅱ DM patients increased. When the blood sugar and TG were higher or complicated with vascular disease, the LPO reaction would be enhanced more markedly. BSHXT will have a good prospect in the prevention and treatment of DM patients complicated with vascular disease.