Effect of Semen Persicae Extract Combined with Cultured Cordyceps on Reversing Capillarization of Sinusoids in Patients with Hepato-Cirrhosis

摘要

Objective: To evaluate the effect of Semen Persicae combined with cultured Cordyceps on Reversing Capillarization of Sinusoids in patients with hepato-cirrhosis. Methods: Forty-four patients were treated for 3 months , the clinical and pathological effects were observed. Results: Patients were improved clinically. Pathological examination on liver biopsy of 6 patients also showed improvement in of Capillarization of sinusoid, which mainly manifested by reduction of enlarged interhepatocellular spaces and collagen fiber in it, increase of lipid droplets within fat-storing cells (FSC), and decrease of proliferation of Kupffer cells. Conclusion: The combined treatment used could reverse the Capillarization of sinusoid, and the mechanism might be related with its inhibition on activity and function of FSC.