Effects of 24 Chinese Medicinal Herbs on Nucleic Acid, Protein and Cell Cycle of Human Lung Adenocarcinoma Cells

摘要

Objective: To study the effects of 24 Chinese medicinal herbs on nucleic acid, protein and cell cycle of human lung adenocarcinoma cells. Methods: Using flow cytometry the authors analysed the effects of 24 Chinese medicinal herbs (CMH) in compound recipe on proliferation index (PI) , DNA index, protein index and ratio of various phases in cell cycle of human lung adenocarcinoma cells (SPC-A-1). Results: The PI was more than 20%, in 4 CMH, while 3 CMH, Gynostemma Pentaphylla, Radix Glehnia, and Radix Ginseng could strengthen the body resistance. That suggested using CMH of strengthening body resistance could not only serve as conventional tonic but also as tumor cell inhibitor. Meanwhile the action points of 24 CMH on cell cycle were different from one another. Conclusions: According to these results, Chinese recipes were more effective in clinical practice.