Tandem reactions of cis-2-acyl-1-alkynyl-1-aryl cyclopropanes tuned by gold(I) and silver(I) catalysts: efficient synthesis of pyran-fused indene cores and 2,4,6-trisubstituted phenols

摘要

Tandem reactions of cis-2-acyl-1-alkynyl-1-aryl cyclopropanes 1 tuned by gold(I) and silver(I) catalysts are described, which afford selectively the key pyran-fused indene cores 2 and the 2,4,6-trisubstituted phenols 3 in good yields, respectively.rnGold- or silver-catalyzed reactions have recently received increasing attention from chemists. These metal catalysts have shown their exceptional ability to activate the alkynyl species, among which, carbonyl alkync-involved transformations have taken a particularly important part in developing synthetic methodologies for the construction of furans, 3(2H)-furanones, functionalized aromatic compounds, as well as 1-allenylisochromenes.