顺-1-苯甲酰基-2-芳基取代的环丙烷衍生物的立体选择性合成

摘要

烯烃与苯甲酰基亚甲基三苯基胂(1)反应,顺利生成顺-1-苯甲酰基-2-芳基取代的环丙烷衍生物.反应不生成反式异构体.副产物三苯基胂可回收.如改用叶立德(1)对应的溴盐,在四氢呋喃或乙腈中于K2OO3存在下反应可获得相同的产物.%cis-1-Benzoyl-2-aryl substituted cyclopropane derivatives are prepared from alkene and benzoylmethylenetriphenylarsine (1). No trans isomer is found in the reaction and triphenylarsorane can be recovered as a byproduct. Same result is obtained when corresponding bromide of ylide 1 is used in the presence of K2CO3 in tetrahydrofuran or acetonitrile.