Facile preparation of amine and amino acid adducts of [60]fullerene using chlorofullerene C_(60)Cl-(6) as a precursor

摘要

We report a general synthetic approach to the preparation of highly functionalized amine and amino acid derivatives of [60]fullerene starting from readily available chlorofullerene C_(60)Cl_6,. The synthesized water-soluble amino acid derivative of C_(60) demonstrated pronounced antiviral activity, while the cationic amine-based compound showed strong antibacterial action in vitro.