Significance of myoglobin as an oxygen store and oxygen transporter in the intermittently perfused human heart: a model study

摘要

Aims The mechanisms by which the left ventricular wall escapes anoxia during the systolic phase of low blood perfusion are investigated, especially the role of myoglobin (Mb), which can (i) store oxygen and (ii) facilitate intracellular oxygen transport. The quantitative role of these two Mb functions is studied in the maximally working human heart.