The expression of hTERT mRNA and cellular immunity in gastric cancer and precancerosis

摘要

CONCLUSION: The expression of telomerase may be a crucial step in gastric carcinogenesis and increased hTERT mRNA may serve as a novel marker for diagno- sis of GC. The immune state of patients with GC and precancerosis was somewhat depressed, which indi- cates the importance of cellular immunological assays in cancer patients. AIM: To observe the expression of Human telomerase reverse transcriptase (hTERT) in gastric carcinomas and precancerosis lesions, to evaluate the immune state of such patients, and to then study the clinical significance of hTERT and immune state for the diagnosis, treat- ment and prognosis of gastric cancer.