Long-Term Follow-up Study of a Prospective Multicenter Sentinel Node Trial: Molecular Detection of Breast Cancer Sentinel Node Metastases

摘要

Background This prospective multicenter sentinel lymph node (SLN) trial investigated whether molecular analysis would improve the detection of SLN metastases and their prognostic value. We report mammaglobin quantitative real-time polymerase chain reaction (qRT-PCR) results and clinical outcome for 547 patients (mean follow-up 7 years).