Relation of Actinic Keratosis to Squamous or Basal Cell Carcinoma/IN REPLY

摘要

Actually, based on my personal experience during 45 years of practice, basal cell carcinoma is at least 10 times more likely to result from actinic keratosis of the face or ears (squamous cell carcinoma of the lower lip is almost always found in cigarette smokers). Basal cell carcinomas, squamous cell carcinomas, and actinic keratosis share common risk factors, such as age, sex, location of residency, occupation (indoor versus outdoor), and propensity to sunburn.1 Dr. Pentecost makes an excellent clinical point that an actinic keratosis lesion often overlies a basal carcinoma lesion.2,3 In addition, basal cell carcinomas are a far more common form of non-melanoma skin cancer than squamous cell carcinomas (80 versus 19 percent, respectively).