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A low frequency of pancreatic islet insulin-expressing cells derived from cord blood stem cell allografts in humans

机译：人脐带血干细胞同种异体移植物中胰岛胰岛素表达细胞的频率低

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摘要

Aims/hypothesisWe sought to establish if stem cells contained in cord blood cell allografts have the capacity to differentiate into insulin-expressing beta cells in humans.

机译：目的/假设我们试图确定脐带血同种异体移植物中所含的干细胞是否具有分化为人类表达胰岛素的β细胞的能力。

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期刊名称 Springer Open Choice
作者
C. J. Huang; A. E. Butler; A. Moran; P. N. Rao; J. E. Wagner; B. R. Blazar; R. A. Rizza; J. C. Manivel; P. C. Butler;
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作者单位

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年(卷),期 -1(54),5
年度 -1
页码 1066–1074
总页数 9
原文格式 PDF
正文语种
中图分类外科学;
关键词
Beta cell Cord blood cell Diabetes Stem cell;

机译：Beta细胞;脐带血细胞;糖尿病;干细胞;

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专利

1. A low frequency of pancreatic islet insulin-expressing cells derived from cord blood stem cell allografts in humans [J] . C. J. Huang, A. E. Butler, A. Moran, Diabetologia . 2011,第5期

机译：人脐带血干细胞同种异体移植物中胰岛胰岛素表达细胞的频率低
2. Adult muscle-derived stem cells engraft and differentiate into insulin-expressing cells in pancreatic islets of diabetic mice [J] . Violeta Mitutsova, Wendy Wai Yeng Yeo, Romain Davaze, Stem Cell Research & Therapy . 2017,第1期

机译：成年肌肉来源的干细胞在糖尿病小鼠的胰岛中植入并分化为表达胰岛素的细胞
3. Islet Neogenesis Associated Protein (INGAP) induces the differentiation of an adult human pancreatic ductal cell line into insulin-expressing cells through stepwise activation of key transcription factors for embryonic beta cell development [J] . Assouline-Thomas Beatrice, Ellis Daniel, Petropavlovskaia Maria, Differentiation: The Journal of the International Society of Differentiation . 2015,第4a5期

机译：胰岛新生关联蛋白（INGAP）通过逐步激活胚胎β细胞发育的关键转录因子来诱导成年人类胰腺导管细胞系分化为表达胰岛素的细胞
4. Selection and Preparation of the Multi-component Cryoprotectant Agent for Vitrification of Hematopoietic Stem/Progenitor Cells Derived from Human Umbilical Cord Blood [C] . Zeljka Bosnjak, rnFrederic Daigne, rnGuillatume Dubus Asian Pacific Confederation of Chemical Engineering congress . 2008

机译：用于人脐带血造血干/祖细胞玻璃化的多组分抗冻剂的选择与制备
5. The characterization and transplantation of human embryonic stem cell-derived motor neuron progenitors following bilateral cervical spinal cord injury. [D] . Rossi, Sharyn Lee. 2010

机译：人胚胎干细胞衍生的运动神经元祖细胞在双侧颈脊髓损伤后的特征和移植。
6. Adult muscle-derived stem cells engraft and differentiate into insulin-expressing cells in pancreatic islets of diabetic mice [O] . Violeta Mitutsova, Wendy Wai Yeng Yeo, Romain Davaze, 2017

机译：成年肌肉来源的干细胞在糖尿病小鼠的胰岛中植入并分化为表达胰岛素的细胞
7. A low frequency of pancreatic islet insulin-expressing cells derived from cord blood stem cell allografts in humans [O] . C. J. Huang, A. E. Butler, A. Moran, 2011

机译：人脐带血干细胞同种异体移植物中胰岛胰岛素表达细胞的频率低
8. Engineering Robust and Functional Vascular Networks in Vivo with Human Adult and Cord Blood-Derived Progenitor Cells [R] . Melero-Martin, J. M., Bischoff, J. 2008

机译：利用人类成人和脐带血衍生祖细胞在体内工程稳健和功能性血管网络

A low frequency of pancreatic islet insulin-expressing cells derived from cord blood stem cell allografts in humans

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