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Comparison of PET imaging with a 68Ga-labelled PSMA ligand and 18F-choline-based PET/CT for the diagnosis of recurrent prostate cancer

机译：PET成像与68Ga标记的PSMA配体和18F-胆碱基PET / CT的比较用于诊断复发性前列腺癌

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摘要

PurposePositron emission tomography (PET) with choline tracers has found widespread use for the diagnosis of prostate cancer (PC). However, choline metabolism is not increased in a considerable number of cases, whereas prostate-specific membrane antigen (PSMA) is overexpressed in most PCs. Therefore, a ⁶⁸Ga-labelled PSMA ligand could be superior to choline tracers by obtaining a high contrast. The aim of this study was to compare such a novel tracer with standard choline-based PET/CT.

机译：目的使用胆碱示踪剂的正电子发射断层扫描（PET）已广泛用于诊断前列腺癌（PC）。但是，在许多情况下，胆碱的代谢并未增加，而在大多数PC中，前列腺特异性膜抗原（PSMA）却过表达。因此，通过获得高对比度，^{68 Ga标记的PSMA配体可能优于胆碱示踪剂。这项研究的目的是将这种新型示踪剂与基于标准胆碱的PET / CT进行比较。}

著录项

期刊名称 Springer Open Choice
作者
Ali Afshar-Oromieh; Christian M. Zechmann; Anna Malcher; Matthias Eder; Michael Eisenhut; Heinz G. Linhart; Tim Holland-Letz; Boris A. Hadaschik; Frederik L. Giesel; Jürgen Debus; Uwe Haberkorn;
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作者单位

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年(卷),期 -1(41),1
年度 -1
页码 11–20
总页数 10
原文格式 PDF
正文语种
中图分类外科学;
关键词
Prostate cancer PET/CT Positron emission tomography PSMA Choline;

机译：前列腺癌;PET / CT;正电子发射断层扫描;PSMA;胆碱;

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专利

1. Comparison of PET imaging with a 68Ga-labelled PSMA ligand and 18F-choline-based PET/CT for the diagnosis of recurrent prostate cancer [J] . Afshar-OromiehA., ZechmannC.M., MalcherA., European Journal of Nuclear Medicine and Molecular Imaging . 2014,第1期

机译：PET成像与68Ga标记的PSMA配体和18F-胆碱基PET / CT的比较，用于诊断复发性前列腺癌
2. Comparison of PET/CT and PET/MRI hybrid systems using a 68Ga-labelled PSMA ligand for the diagnosis of recurrent prostate cancer: Initial experience [J] . Afshar-OromiehA., HaberkornU., SchlemmerH.P., European Journal of Nuclear Medicine and Molecular Imaging . 2014,第5期

机译：使用68Ga标记的PSMA配体对PET / CT和PET / MRI混合系统进行比较以诊断复发性前列腺癌的初步经验
3. Comparison of PET imaging with a 68Ga-labelled PSMA ligand versus 18F-choline PET/CT for the diagnosis of Prostate Cancer & Radioprotection for involved personnel [J] . Zeinab Khansa, Mohamad B. Haidar, Nemer Neaimeh, Health and technology. . 2019,第4期

机译：宠物成像与68GA标记的PSMA配体对18F-Choline PET / CT进行比较，用于诊断涉及人员的前列腺癌和辐射防护
4. Automation of population-based recurrence map for PSMA-PET prostate cancer patients after prostatectomy [C] . Bastien Rigaud, Pascale Beliveau, Guillaume Cazoulat, Conference on Medical Imaging: Image Processing . 2021

机译：PSMA-PET前列腺癌前列腺切除术中患者的群体复发图自动化
5. The development of a versatile and expeditious route to PET imaging ligands and its potential applications to prostate cancer treatment and diagnosis. [D] . Ng, Patrick Chow Yuen. 2010

机译：PET成像配体的通用快速开发途径及其在前列腺癌治疗和诊断中的潜在应用。
6. The diagnostic value of PET/CT imaging with the 68Ga-labelled PSMA ligand HBED-CC in the diagnosis of recurrent prostate cancer [O] . Ali Afshar-Oromieh, Eleni Avtzi, Frederik L. Giesel, -1

机译：带有68Ga标记的PSMA配体HBED-CC的PET / CT成像对复发性前列腺癌的诊断价值
7. Comparison of PET imaging with a 68Ga-labelled PSMA ligand and 18F-choline-based PET/CT for the diagnosis of recurrent prostate cancer [O] . Ali Afshar-Oromieh, Christian M. Zechmann, Anna Malcher, 2013

机译：PET成像与68Ga标记的PSMA配体和18F-胆碱基PET / CT的比较，用于诊断复发性前列腺癌

Comparison of PET imaging with a 68Ga-labelled PSMA ligand and 18F-choline-based PET/CT for the diagnosis of recurrent prostate cancer

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