Clinical usefulness of urinary liver-typefatty-acid-binding protein as a perioperative marker of acute kidney injury inpatients undergoing endovascular or open-abdominal aortic aneurysmrepair

摘要

PurposeAcute kidney injury (AKI) is common after cardiovascular surgery and is usually diagnosed on the basis of the serum creatinine (SCr) level and urinary output. However, SCr is of low sensitivity in patients with poor renal function. Because urinary liver-type fatty-acid-binding protein (L-FABP) reflects renal tubular injury, we evaluated whether perioperative changes in urinary L-FABP predict AKI in the context of abdominal aortic repair.