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Laser tracheobronchoplasty: a novel technique for the treatment of symptomatic tracheobronchomalacia

机译:激光气管支气管成形术:一种新技术用于治疗有症状的气管支气管软化症

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摘要

The management of tracheobronchomalacia is a very challenging problem with few treatment options. This study aims to evaluate the outcomes of a novel surgical treatment for membranous tracheobronchomalacia. A consecutive series of patients with tracheobronchomalacia were treated with two to three holmium laser scarring surgeries of the hyperdynamic tracheal and bronchial walls for the purpose of stiffening them through fibrosis. Patients filled out a Dyspnea Index questionnaire before and after treatment. Ten patients were treated for their tracheobronchomalacia with a mean age of 54 years. Symptoms included severe dyspnea, dry cough, recurrent pulmonary infections, and respiratory failure. Fifty percent of patients presented with wheezing refractory to traditional treatment. Tracheobronchomalacia was associated with gastroesophageal reflux disease (n = 8), obstructive sleep apnea (n = 5), and tracheal stenosis (n = 3). Only 50 % of patients presented with morbid obesity. All cases showed significant improvement of their respiratory symptoms with a mean postoperative difference of 22.3 out of a maximum impairment score of 40 (P < 0.01) on the Dyspnea Index. The mean number of procedures was 2.3 per patient with the average laser energy delivered per procedure of 1600 J. Laser tracheobronchoplasty is a safe, easy to adopt, and effective technique for the treatment of membranous tracheobronchomalacia. It presents a simple alternative to the commonly used procedures like endoluminal stenting and open tracheobronchoplasty.Electronic supplementary materialThe online version of this article (doi:10.1007/s00405-016-4349-y) contains supplementary material, which is available to authorized users.
机译:气管支气管软化症的治疗是极富挑战性的问题,几乎没有治疗选择。这项研究旨在评估膜性气管支气管软化的新型外科治疗的结果。连续的一系列气管支气管软化症患者接受了2到3次dynamic气动力化气管壁和支气管壁的laser激光瘢痕手术,目的是通过纤维化使其硬化。患者在治疗前后填写呼吸困难指数问卷。十名患者接受了气管支气管软化治疗,平均年龄为54岁。症状包括严重的呼吸困难,干咳,反复出现肺部感染和呼吸衰竭。 50%的患者表现为传统治疗难治性喘息。气管支气管软化症与胃食管反流疾病(n = 8),阻塞性睡眠呼吸暂停(n = 5)和气管狭窄(n = 3)相关。仅50%的患者出现病态肥胖。所有病例呼吸困难指数均得到显着改善,呼吸困难指数的最大障碍评分为40(P <0.01),平均术后差异为22.3。每位患者的平均手术数为2.3,每手术平均释放的激光能量为1600J。激光气管支气管成形术是一种安全,易于采用且有效的治疗膜性气管支气管软化症的技术。它提供了一种常用方法的简单替代方法,例如腔内支架植入术和开放式气管支气管成形术。电子补充材料本文的在线版本(doi:10.1007 / s00405-016-4349-y)包含补充材料,授权用户可以使用。

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