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A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models

机译:基于新颖的基于多孔介质的一维动脉​​血流模型流出边界阻力方法

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摘要

In this paper we introduce a novel method for prescribing terminal boundary conditions in one-dimensional arterial flow networks. This is carried out by coupling the terminal arterial vessel with a poro-elastic tube, representing the flow resistance offered by microcirculation. The performance of the proposed porous media-based model has been investigated through several different numerical examples. First, we investigate model parameters that have a profound influence on the flow and pressure distributions of the system. The simulation results have been compared against the waveforms generated by three elements (RCR) Windkessel model. The proposed model is also integrated into a realistic arterial tree, and the results obtained have been compared against experimental data at different locations of the network. The accuracy and simplicity of the proposed model demonstrates that it can be an excellent alternative for the existing models.
机译:在本文中,我们介绍了一种在一维动脉流动网络中规定终端边界条件的新方法。这是通过将末端动脉血管与孔隙弹性管耦合来实现的,该孔隙弹性管代表了微循环所提供的流动阻力。通过几个不同的数值示例研究了所提出的基于多孔介质的模型的性能。首先,我们研究对系统流量和压力分布有深远影响的模型参数。已将仿真结果与由三个元素(RCR)Windkessel模型生成的波形进行了比较。所提出的模型也被集成到了现实的动脉树中,并且将获得的结果与网络不同位置的实验数据进行了比较。所提出模型的准确性和简单性表明,它可以作为现有模型的绝佳替代品。

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