A new hydrophilic polysulfone hemodialysis membrane can prevent platelet–neutrophil interactions and successive neutrophil activation

摘要

Purpose:Microaggregates have often been observed during hemodialysis and are clearly associated with complications of hemodialysis therapy. In this study, we aimed to clarify the effects of two polysulfone membranes, with different abilities to activate blood cells, on the formation of these microaggregates; we also investigated their molecular mechanisms.