Parallel Information Processing in Motor Systems: Intracerebral Recordings of Readiness Potential and CNV in Human Subjects

摘要

We performed intracerebral recordings of Readiness Potential (RP) and Contingent Negative Variation (CNV) with simple repetitive distal limb movement in candidates for epilepsy surgery. In 26 patients (in Paris), depth electrodes were located in various cortical structures; in eight patients (in Brno), in the basal ganglia and the cortex. RPs were displayed in the conteral primary motor cortex, conteral somato-sensory cortex, and bilaterally in the SMA and the caudal part of the anterior cingulate cortices. CNVs were recorded in the same cortical regiom as the RP, as well as in the ipsilateral primary motor cortex, and bilaterally in the premotor fronto-lateral, parietal superior, and middle temporal regions. In the basal ganglia, the RP was recorded in the putamen in six of seven patients, and in the head of the caudatenucleus and the pallidum in the only patient withelectrodes in these recording sites. We suggest thatour results are consistent with a long-lasting,simultaneous activation of cortical and subcorticalstructures, before and during self-paced andstimulus-triggered movements. The particularregiom that are simultaneously active may bedetermined by the task context.