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Thermoreversible Pluronic® F127-based hydrogel containing liposomes for the controlled delivery of paclitaxel: in vitro drug release cell cytotoxicity and uptake studies

机译：基于Pluronic®F127的可逆热凝胶含脂质体可控制紫杉醇的递送：体外药物释放细胞毒性和吸收研究

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PurposeTo develop an in situ gel system comprising liposome-containing paclitaxel (PTX) dispersed within the thermoreversible gel (Pluronic^® F127 gel) for controlled release and improved antitumor drug efficiency.

机译：目的开发包含分散在热可逆凝胶（Pluronic ^{® F127凝胶）中的含脂质体的紫杉醇（PTX）的原位凝胶系统，以控制释放并提高抗肿瘤药物的效率。}

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期刊名称 International Journal of Nanomedicine
作者
Shufang Nie; WL Wendy Hsiao; Weisan Pan; Zhijun Yang;
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作者单位

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年(卷),期 2011(6),-1
年度 2011
页码 151–166
总页数 16
原文格式 PDF
正文语种
中图分类生化遗传学;生化药理学;
关键词
controlled release cytotoxicity evaluation drug uptake;

机译：控释;细胞毒性评估;药物吸收;

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专利

1. Thermoreversible Pluronic? F127-based hydrogel containing liposomes for the controlled delivery of paclitaxel: in vitro drug release, cell cytotoxicity, and uptake studies [J] . Shufang Nie, WL Wendy Hsiao, Weisan Pan, International Journal of Nanomedicine . 2011,第6期

机译：热可逆Pluronic？含F127的水凝胶脂质体，用于紫杉醇的受控递送：体外药物释放，细胞毒性和吸收研究
2. The drug encapsulation efficiency, in vitro drug release, cellular uptake and cytotoxicity of paclitaxel-loaded poly(lactide)-tocopheryl polyethylene glycol succinate nanoparticles. [J] . Zhang Z, Feng SS Biomaterials . 2006,第21期

机译：紫杉醇负载的聚（丙交酯）-生育酚聚乙二醇琥珀酸酯纳米颗粒的药物封装效率，体外药物释放，细胞摄取和细胞毒性。
3. Magnolol-loaded core-shell hydrogel nanoparticles: drug release, intracellular uptake, and controlled cytotoxicity for the inhibition of migration of vascular smooth muscle cells. [J] . Wang YJ, Chien YC, Wu CH, Molecular pharmaceutics . 2011,第6期

机译：厚朴酚负载的核壳水凝胶纳米颗粒：药物释放，细胞内摄取和可控制的细胞毒性，可抑制血管平滑肌细胞的迁移。
4. Slow Controlled Release of Anticancer Drugs with Thermoresponsive and Injectable Pluronic F127-based Biodegradable Hydrogel [C] . Tzu-Wei Wang, Hsi-Chin Wu, Ying-Yu Chen World biomaterials congress . 2012

机译：具有热响应性和可注射的基于Pluronic F127的生物可降解水凝胶的抗癌药物的缓慢控制释放
5. Computational and experimental studies of controlled release drug delivery: Effect of microsphere diameter and drug size on in-vitro release kinetics. [D] . Raman, Chandrashekar. 2005

机译：控释药物递送的计算和实验研究：微球直径和药物大小对体外释放动力学的影响。
6. Effect of a controlled-release drug delivery system made of oleanolic acid formulated into multivesicular liposomes on hepatocellular carcinoma in vitro and in vivo [O] . Yuling Luo, Zhongbing Liu, Xiaoqin Zhang, 1988

机译：由齐墩果酸制成多囊脂质体的控释给药系统对肝癌的体内外影响
7. Thermoreversible Pluronic® F127-based hydrogel containing liposomes for the controlled delivery of paclitaxel: in vitro drug release, cell cytotoxicity, and uptake studies [O] . Nie, Shufang, Hsiao, WL Wendy, Pan, Weisan, 2011

机译：基于Pluronic®F127的可逆热凝胶，含脂质体，可控制紫杉醇的递送：体外药物释放，细胞毒性和吸收研究

Thermoreversible Pluronic® F127-based hydrogel containing liposomes for the controlled delivery of paclitaxel: in vitro drug release cell cytotoxicity and uptake studies

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