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Multiblock biodegradable hydrogels for use as a tissue treatment drug release and drug controlled for drug delivery

机译:多嵌段可生物降解水凝胶,用作组织治疗药物的释放和药物控制的药物输送

摘要

Gel-forming macromers including a crosslinkable group (57) at least one contains a block polymer of at least four [Abstract], at least two of them is and hydrophobicity, but and are hydrophilic is provided. The covalently cross-linked, these macromers can form a gel in the tissue surface in vivo. Gels formed from macromers are useful in medical applications, including a variety of tissues and drug delivery coating heat sensitive and, and have a combination of properties including lipophilic.
机译:包括可交联基团(57)的至少一个形成凝胶的大分子单体包含至少四个的嵌段聚合物,其至少两个是疏水性的,但提供了亲水性。这些大分子单体通过共价交联可以在体内组织表面形成凝胶。由大分子单体形成的凝胶可用于医疗应用,包括对各种组织和热敏感的药物涂层和药物传递涂层,并具有包括亲脂性在内的多种特性。

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