Five Sesquiterpenoids from a Marine-Derived Fungus Aspergillus sp. Isolated from a Gorgonian Dichotella gemmacea

摘要

Three new phenolic bisabolane-type sesquiterpenoids: (+)-methyl sydowate (>1), 7-deoxy-7,14-didehydrosydonic acid (>2), and 7-deoxy-7,8-didehydrosydonic acid (>3), together with two known fungal metabolites were isolated from the fermentation broth of a marine-derived fungus Aspergillus sp., which was isolated in turn from a gorgonian Dichotella gemmacea collected from the South China Sea. Their structures were elucidated by combined spectroscopic methods, and the structure of >1 was further confirmed by single-crystal X-ray data.