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What are the physical and mental health implications of duration of untreated psychosis?

机译:未经治疗的精神病持续时间有什么身心健康?

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摘要

Psychotic disorders, such as schizophrenia, are among the most severe and debilitating conditions in psychiatry, and in all of medicine. Duration of untreated psychosis (DUP) is the period that goes from the onset of psychosis to the start of an adequate treatment. DUP is an important prognostic factor, as longer DUP has been associated with poor mental health outcomes, including more severe positive and negative symptoms and decreased likelihood of remission [1]. However, DUP has been a source of controversy lately, particularly regarding its relationship with psychosocial functioning, arguably one of the most important mental health outcomes for psychiatric patients along with quality of life. While a longer duration of psychosis has been consistently associated with poor psychosocial functioning, the importance of this initial period until individuals with psychosis get an appropriate treatment (i.e., DUP) has been a subject of discussion. Two main opposed scenarios have been presented:
机译:精神病疾病,如精神分裂症,是精神病学中最严重和最令人衰弱的病症之一,并在所有药物中。未经治疗的精神病(DUP)的持续时间是从精神病发作到足够治疗开始的时期。 DUP是一个重要的预后因素,因为较长的杜佩已经与心理健康状况不佳,包括更严重的阳性和阴性症状,减少缓解的可能性[1]。然而,DUP最近一直是争议的来源,特别是其与心理社会功能的关系,可谓是精神病患者最重要的心理健康成果之一,以及生活质量。虽然长期的精神病持续时间始终与心理社会功能差,但这一初始期限的重要性,直到具有精神病的个人获得适当的治疗(即,DUP)是一个讨论的主题。已经提出了两种主要反对情景:

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