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Pure Large Cell Neuroendocrine Carcinoma of the Ovary with Metastasis to Cervix: A Rare Case Report and Review of Literature

机译:卵巢转移至子宫颈的纯大细胞神经内分泌癌:罕见病例报告及文献复习

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摘要

Ovarian Large Cell Neuroendocrine Carcinoma (LCNEC) is a recently described rare entity, which even more rarely occurs in a ‘pure’ form without any associated surface epithelial-stromal or germ cell component. Cervix metastasis of ovarian LCNEC has not been reported previously. We report here a case of ovarian LCNEC in a 35-year-old female who presented with abdominal pain and amenorrhea. Grossly the left ovary showed a solid cystic tumour measuring 6 cm in diameter. Histological examination showed a pure LCNEC without any associated component, confirmed by immunohistochemistry. Metastatic tumour deposits with numerous lymphovascular emboli were identified in the cervix. A comprehensive review of literature along with the various differential diagnosis is discussed.
机译:卵巢大细胞神经内分泌癌(LCNEC)是最近描述的罕见实体,在没有任何相关的表面上皮基质或生殖细胞成分的情况下,以“纯”形式发生的情况更为罕见。卵巢LCNEC的子宫颈转移尚未见报道。我们在此报告一例35岁女性的腹部LCNEC卵巢疾病,该患者出现腹痛和闭经。左卵巢大体上显示出直径为6 cm的实体囊性肿瘤。组织学检查显示纯LCNEC,无任何相关成分,通过免疫组织化学证实。在子宫颈中发现具有大量淋巴血管栓塞的转移性肿瘤沉积物。讨论文献以及各种鉴别诊断的全面审查。

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