FoxP3+CD4+ IFN-γ+CD4+ and IFN-γ+CD8+ cell levels in erosive and non-erosive types of oral lichen planus patients

摘要

Oral lichen planus (OLP) is a localized autoimmune oral mucosal disease. This study evaluated whether different types of OLP patients including erosive OLP (EOLP), major EOLP, minor EOLP, and non-erosive OLP (NEOLP) patients had significantly higher percentages of FoxP3+CD4+ or IFN-γ+CD4+ cells in total CD4+ cells, and of IFN-γ+CD8+ cells in total CD8+ cells than healthy control subjects and whether the patient's age had significant influences on these cell percentages in OLP patients.