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Prediction of Alternative Drug-Induced Liver Injury Classifications Using Molecular Descriptors Gene Expression Perturbation and Toxicology Reports

机译：使用分子描述夹基因表达扰动和毒理学报告预测替代药物诱导的肝损伤分类

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期刊名称 Frontiers in Genetics
作者
Wojciech Lesiński; Krzysztof Mnich; Witold R. Rudnicki;
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作者单位

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年(卷),期 2021(-1),-1
年度 2021
页码 -1
总页数 11
原文格式 PDF
正文语种
中图分类遗传学;
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机译：机器学习;随机森林;数据集成;药物诱导肝损伤;特征选择;

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专利

1. Gene Expression Data Based Deep Learning Model for Accurate Prediction of Drug-Induced Liver Injury in Advance [J] . Feng Chunlai, Chen Hengwei, Yuan Xianqin, Journal of chemical information and modeling . 2019,第7期

机译：基于基于基于Beain学习模型的准确预测药物诱导肝损伤的深度学习模型
2. Drug-induced liver injury associated with Complementary and Alternative Medicine: a review of adverse event reports in an Asian community from 2009 to 2014 [J] . Desmond Chun Hwee Teo, Patricia Suet Leng Ng, Siew Har Tan, BMC Complementary and Alternative Medicine . 2016,第1期

机译：与补充和替代医学有关的药物性肝损伤：2009年至2014年亚洲社区不良事件报告的回顾
3. Utilization of causal reasoning of hepatic gene expression in rats to identify molecular pathways of idiosyncratic drug-induced liver injury [J] . LaifenfeldD., QiuL., SwissR., Toxicological sciences: An official journal of the Society of Toxicology . 2014,第1期

机译：利用大鼠肝基因表达的因果关系来鉴定特异药物性肝损伤的分子途径
4. A Drug-Induced Liver Injury Prediction Model using Transcriptional Response Data with Graph Neural Network [C] . Doyeong Hwang, Minji Jeon, Jaewoo Kang IEEE International Conference on Big Data and Smart Computing . 2020

机译：基于图谱神经网络的转录反应数据的药物诱导的肝损伤预测模型
5. The computational prediction of continuous and binary toxicological properties for organic molecules from molecular structure and the development of a novel set generation technique for quantitative structure -activity relationships and classification models [D] . Serra, Jon R., Jr. 2004

机译：基于分子结构的有机分子连续和二元毒理学性质的计算预测以及定量结构-活性关系和分类模型的新集合生成技术的发展
6. Molecular Initiating Events Associated with Drug-Induced Liver Malignant Tumors: An Integrated Study of the FDA Adverse Event Reporting System and Toxicity Predictions [O] . Kota Kurosaki, Yoshihiro Uesawa 2021

机译：与药物诱导的肝脏恶性肿瘤相关的分子启动事件：对FDA不良事件报告系统和毒性预测的综合研究
7. Utilization of causal reasoning of hepatic gene expression in rats to identify molecular pathways of idiosyncratic drug-induced liver injury [O] . Daphna Laifenfeld, Luping Qiu, Rachel Swiss, 2016

机译：利用大鼠肝脏基因表达的因果推理鉴定特异性药物性肝损伤的分子途径

Prediction of Alternative Drug-Induced Liver Injury Classifications Using Molecular Descriptors Gene Expression Perturbation and Toxicology Reports

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