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Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose

机译：细胞渗透琥珀酸酯前药中的急性乙酰胍overdose细胞模型中拯救线粒体呼吸

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期刊名称 PLoS ONE
作者
Sarah Piel; Imen Chamkha; Adam Kozak Dehlin; Johannes K. Ehinger; Fredrik Sjövall; Eskil Elmér; Magnus J. Hansson; Jianhua Zhang; Jianhua Zhang; Jianhua Zhang;
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年(卷),期 2020(15),4
年度 2020
页码 e0231173
总页数 16
原文格式 PDF
正文语种
中图分类生物学;
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专利

1. Mitochondrial respiratory chain complex I dysfunction induced by N-methyl carbamate ex vivo can be alleviated with a cell-permeable succinate prodrug [J] . Toxicology in vitro: an international journal published in association with BIBRA . 2020,第期

机译：由N-甲基氨基甲酸酯离体诱导的线粒体呼吸链复合物I功能障碍可以用细胞可渗透的琥珀酸盐前药来缓解
2. Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency [J] . Johannes K. Ehinger, Sarah Piel, Rhonan Ford, Nature Communications . 2016,第1期

机译：细胞可渗透的琥珀酸酯前药绕过线粒体复合体I缺乏
3. In vitro comparison of hydroxocobalamin (B12a) and the mitochondrial directed therapy by a succinate prodrug in a cellular model of cyanide poisoning [J] . Shawn Owiredu, Abhay Ranganathan, John C. Greenwood, Toxicology Reports . 2020,第1期

机译：氰化物中毒细胞模型中琥珀酸前药的体外比较羟钴胺（B12A）和线粒体定向治疗
4. Construction of a Cellular Model for Mitochondrial Dysfunction in Alzheimer's Disease by over Expressing Cyclophilin D [C] . Cong Xiao, Wang Youzheng, Zhang Wensheng 5th International Conference on Bioinformatics and Biomedical Engineering . 2011

机译：通过过度表达亲环素D构建阿尔茨海默氏病线粒体功能障碍细胞模型
5. The Fungicide Maneb Covalently Adducts Highly Reactive Protein Thiols Involved in Both Mitochondrial Respiration and Central Carbon Metabolism in a Toxicant Model of Parkinson’s Disease [D] . Anderson, Colin Christopher. 2021

机译：杀菌剂MANEB在帕金森病的毒物模型中共价加合涉及线粒体呼吸和中央碳代谢的高度反应性蛋白硫醇
6. Cell-Permeable Succinate Rescues Mitochondrial Respiration in Cellular Models of Statin Toxicity [O] . Vlad F. Avram, Imen Chamkha, Eleonor Åsander-Frostner, 2021

机译：细胞可渗透的琥珀酸盐在他汀类药物毒性的细胞模型中拯救线粒体呼吸
7. Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose [O] . Sarah Piel, Imen Chamkha, Adam Kozak Dehlin, 2020

机译：细胞渗透琥珀酸酯前药中的急性乙酰胍overdose细胞模型中拯救线粒体呼吸

Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose

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