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Generation of highly activated antigen-specific tumor-infiltrating CD8+ T cells induced by a novel T cell-targeted immunotherapy

机译：通过新型T细胞靶向免疫疗法诱导的高度活性抗原特异性肿瘤浸润的CD8 + T细胞的产生

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期刊名称 Oncoimmunology
作者
Ava Vila-Leahey; Alecia MacKay; Liliana Portales-Cervantes; Genevieve M. Weir; Alexandra Merkx-Jacques; Marianne M. Stanford;
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年(卷),期 2020(9),1
年度 2020
页码 1782574
总页数 19
原文格式 PDF
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机译：组合免疫疗法;检查点抑制剂;T细胞活化;CD8;

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专利

1. Generation of highly activated, antigen-specific tumor-infiltrating CD8+ T cells induced by a novel T cell-targeted immunotherapy [J] . Vila-Leahey, MacKay, Portales-Cervantes, Oncoimmunology. . 2020,第1期

机译：通过新型T细胞靶向免疫疗法产生高活性的抗原特异性肿瘤浸润的CD8 + T细胞
2. Checkpoint Blockade Immunotherapy Relies on T-bet but Not Eomes to Induce Effector Function in Tumor-Infiltrating CD8+ T Cells [J] . Melissa M. Berrien-Elliott, Jinyun Yuan, Lauryn E. Swier, Cancer immunity . 2015,第2期

机译：检查点封锁免疫疗法依赖于T-bet，但不能诱导肿瘤浸润性CD8 + T细胞的效应子功能。
3. Rescue of Notch-1 Signaling in Antigen-Specific CD8+ T Cells Overcomes Tumor-Induced T-cell Suppression and Enhances Immunotherapy in Cancer [J] . Rosa A. Sierra, Paul Thevenot, Patrick L. Raber, Cancer immunity . 2014,第8期

机译：抗原特异性CD8 + T细胞中Notch-1信号的挽救克服了肿瘤引起的T细胞抑制并增强了癌症的免疫疗法。
4. Nanostructural and biochemical property changes in activation-induced CD8+ T cell apoptosis utilizing AFM and Raman spectroscopy [C] . Y.J. Lee, G.J. Lee, H.K. Park National SBIR/STTR conference;Annual nanotech conference and expo;Annual TechConnect world innovation conference expo . 2016

机译：利用原子力显微镜和拉曼光谱研究激活诱导的CD8 + T细胞凋亡的纳米结构和生化特性变化
5. Provision of antigen-specific CD4+ T cells prevents the tolerization of CD8+ tumor-specific T cells in a mouse model of prostate cancer. [D] . Shafer-Weaver, Kimberly Ann. 2009

机译：提供抗原特异性CD4 + T细胞可防止在前列腺癌的小鼠模型中耐受CD8 +肿瘤特异性T细胞。
6. Checkpoint blockade immunotherapy relies on T-bet but not Eomes to induce effector function in tumor-infiltrating CD8+ T cells [O] . Melissa M. Berrien-Elliott, Jinyun Yuan, Lauryn E. Swier, -1

机译：检查点封锁免疫疗法依赖T-bet而非Eomes诱导肿瘤浸润性CD8 + T细胞的效应子功能
7. Checkpoint Blockade Immunotherapy Relies on T-bet but Not Eomes to Induce Effector Function in Tumor-Infiltrating CD8+ T Cells [O] . Melissa M. Berrien-Elliott, Jinyun Yuan, Lauryn E. Swier, 2014

机译：检查点阻断免疫疗法依赖于T-BET但不是浓度诱导肿瘤浸润CD8 + T细胞的效应功能
8. Visualizing Breast Cancer Cell Interaction With Tumor-Infiltrating Lymphocytes During Immunotherapy [R] . Beuneu, H, Demaria, S, Dustin, M, 2014

机译：在免疫治疗期间可视化乳腺癌细胞与肿瘤浸润淋巴细胞的相互作用

Generation of highly activated antigen-specific tumor-infiltrating CD8+ T cells induced by a novel T cell-targeted immunotherapy

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