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Mitotic stress-induced secretome primes cancer cells to apoptosis and maximizes paclitaxel response in breast tumors when combined with BCL-xL-targeting BH3 mimetics

机译：有丝分裂应激诱导的秘密素癌细胞在结合Bcl-XL靶向BH3模拟物时使乳腺肿瘤中的癌细胞最大化最大化紫杉醇反应

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期刊名称 Molecular Cellular Oncology
作者
Steven Lohard; Philippe P. Juin; Sophie Barillé-Nion;
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作者单位

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年(卷),期 2020(7),3
年度 2020
页码 1735912
总页数 3
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词

机译：抗胺;BH3模拟物;炎症沉淀;凋亡灌注;

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专利

1. Combined bazedoxifene and paclitaxel treatments inhibit cell viability, cell migration, colony formation, and tumor growth and induce apoptosis in breast cancer [J] . Fu Shengling, Chen Xiang, Lo Hui-Wen, Cancer letters . 2019,第期

机译：结合苯胺酶和紫杉醇处理抑制细胞活力，细胞迁移，菌落形成和肿瘤生长，诱导乳腺癌凋亡
2. Interference with the HSF1/HSP70/BAG3 Pathway Primes Glioma Cells to Matrix Detachment and BH3 Mimetic-Induced Apoptosis [J] . Antonietti Patrick, Linder Benedikt, Hehlgans Stephanie, Molecular cancer therapeutics . 2017,第1期

机译：干扰HSF1 / HSP70 / BAG3途径将胶质瘤细胞引发至基质脱离和BH3仿真诱导的细胞凋亡
3. The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein–protein interactions with Bak [J] . Xiaobo Cao, Jeremy L Yap, M Karen Newell-Rogers, Molecular Cancer . 2013,第1期

机译：新型的BH3α-螺旋模拟物JY-1-106通过破坏Bcl-xL和Mcl-1蛋白与Bak的蛋白相互作用，诱导一部分癌细胞（肺癌，结肠癌和间皮瘤）凋亡
4. Proteomic Profiling of Breast Cancer Cell Line Secretome for Basal-type Specific Tumor Biomarker Discovery Using Skyline MS1 Filtering [C] . Anna M. Zawadzka, Birgit Schilling, Michael Cusack, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2013

机译：基础型特异性肿瘤生物标志物发现使用天际线MS1过滤的基础型特异性肿瘤生物标志物发现的蛋白质组学分析
5. Valspodar restores paclitaxel-induced apoptosis in the adriamycin-resistant human breast cancer cell line MCF7/adr*. [D] . Chadderton, Antony Robert. 2003

机译：Valspodar可在耐阿霉素的人乳腺癌细胞MCF7 / adr *中恢复紫杉醇诱导的凋亡。
6. Targeting of apoptotic pathways by SMAC or BH3 mimetics distinctly sensitizes paclitaxel-resistant triple negative breast cancer cells [O] . Effrosini G. Panayotopoulou, Anna-Katharina Müller, Melanie Börries, 1974

机译：通过SMAC或BH3模拟物靶向凋亡途径可明显增强抗紫杉醇的三阴性乳腺癌细胞的敏感性
7. Mitotic stress-induced secretome primes cancer cells to apoptosis and maximizes paclitaxel response in breast tumors when combined with BCL-xL-targeting BH3 mimetics [O] . Steven Lohard, Philippe P. Juin, Sophie Barillé-Nion 2020

机译：有丝分裂应激诱导的秘密素癌细胞在结合Bcl-XL靶向BH3模拟物时使乳腺肿瘤中的癌细胞最大化，最大化紫杉醇反应
8. Differentiation, early response gene expression, and apoptosis induction in human breast tumor cells by Okadaic Acid and related inhibitors of protein phosphatases 1 and 2A. Okadaic acid effects on human breast tumor cells [R] . Kiguchi, K. , Giometti, C. , Chubb, C. H. , 1992

机译：冈田酸和蛋白磷酸酶1和2a的相关抑制剂在人乳腺肿瘤细胞中的分化，早期反应基因表达和凋亡诱导。冈田酸对人乳腺癌细胞的影响

Mitotic stress-induced secretome primes cancer cells to apoptosis and maximizes paclitaxel response in breast tumors when combined with BCL-xL-targeting BH3 mimetics

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