Identifying the novel key genes in renal cell carcinoma by bioinformatics analysis and cell experiments

摘要

Identification of consistent DEGs in RCC. a Venn plot for consistent DEGs among the mRNA expression profiling sets {"type":"entrez-geo","attrs":{"text":"GSE781","term_id":"781"}}GSE781, {"type":"entrez-geo","attrs":{"text":"GSE68417","term_id":"68417"}}GSE68417, {"type":"entrez-geo","attrs":{"text":"GSE6344","term_id":"6344"}}GSE6344, {"type":"entrez-geo","attrs":{"text":"GSE53000","term_id":"53000"}}GSE53000. b The PPI network of DEGs was constructed using Cytoscape. c The most significant module was obtained from PPI network. d Hub genes and their co-expression genes were analyzed using cBioPortal. e The biological process analysis of hub genes was constructed. f Hierarchical clustering of hub genes was constructed using UCSC