Subcutaneous sarcoidosis: a report of 13 cases and its association with extracutaneous sarcoidosis

摘要

Sarcoidosis is a systemic granulomatous disorder, mainly involving the lung, eye, and skin. Cutaneous sarcoidosis accounts for 20-35% of sarcoidosis patients, with different ratios depending on race (1-3). Cutaneous manifestations of sarcoidosis exhibit specific and non-specific lesions. Specific lesions histologically show non-caseating epithelioid cell granulomas, and the clinical features include papules, nodules, plaques, scars, lupus pernio, as well as various rare forms such as erythema nodosum-like, psoriasiform, ulcerative, and ichthyosiform lesions (3,4). By contrast, a representative of the non-specific lesions, which lack sarcoidal granulomas histologically, is erythema nodosum. Subcutaneous sarcoidosis is one of a rare form of cutaneous sarcoidosis, and studies with large study populations are few (5-8). Herein, we report 13 cases of subcutaneous sarcoidosis which we experienced in our department over a period of ten years.