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Noninvasive Tests (NITs) for Hepatic Fibrosis in Fatty Liver Syndrome

机译:脂肪肝综合征中肝纤维化的非侵袭性试验(NITS)

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摘要

Fatty liver syndrome is an emerging health problem in the world, due to the high prevalence of obesity and alcohol use disorder. Given the nature of the disease’s advancement to cirrhosis and liver-related complications, it is important to assess the severity of the disease, which is typically done via a liver biopsy. Due to the limitations and risks of liver biopsy, the role of noninvasive tests is essential and evolving to stratify the stage of the liver disease, predict the outcomes, and/or monitor the treatment response. This review is focused on noninvasive tests, including the use of serum-based biomarkers, ultrasound-based shear wave elastography, transient elastography, and magnetic resonance elastography in both clinical and research settings.
机译:由于肥胖和酒精使用障碍的高度普及,脂肪肝综合征是世界上的新兴健康问题。鉴于疾病对肝硬化和肝脏相关并发症的进步的性质,评估疾病的严重程度是重要的,这通常通过肝脏活组织检查完成。由于肝脏活检的局限性和风险,非侵入性试验的作用是必不可少的,而不断发展,以分层肝病的阶段,预测结果和/或监测治疗反应。本综述专注于非侵入性测试,包括使用血清基生物标志物,超声型剪力波弹性摄影,瞬态弹性造影和磁共振弹性术在临床和研究中。

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