The DDX39B/FUT3/TGFβR-I axis promotes tumor metastasis and EMT in colorectal cancer

摘要

A DDX39B/BAT1 expression in COAD (different histological types and cancer stages from the TCGA Dataset) and normal tissues (unpaired). B, C DDX39B expression in paired COAD/READ and normal tissues (TCGA Database, n = 26 = 6). D Overall survival with low/high DDX39B expression, obtained from a colorectal cancer set of {"type":"entrez-geo","attrs":{"text":"GSE17538","term_id":"17538"}}GSE17538. E DDX39B mRNA expression in colorectal cancer tissues and paired non-cancerous tissues (n = 74). F DDX39B protein expression in nine paired colorectal cancer and normal tissues. G IHC analysis of paired colorectal cancer and adjacent non-tumor tissues; scale bars, 20/50 μm. COAD colon adenocarcinoma, READ rectum adenocarcinoma.