首页> 外国专利> COMPOSITION FOR ANALYZING ACTIVITY OF MAEC WHICH PROMOTES METASTASIS OF COLORECTAL CANCER BY MEASURING EXPRESSION LEVEL OF MIC-1 AND METHOD FOR ANALYZING ACTIVITY OF MAEC WHICH PROMOTES METASTASIS OF COLORECTAL CANCER USING SAME

COMPOSITION FOR ANALYZING ACTIVITY OF MAEC WHICH PROMOTES METASTASIS OF COLORECTAL CANCER BY MEASURING EXPRESSION LEVEL OF MIC-1 AND METHOD FOR ANALYZING ACTIVITY OF MAEC WHICH PROMOTES METASTASIS OF COLORECTAL CANCER USING SAME

机译:通过测量MIC-1的表达水平分析促进大肠癌转移的MAEC活性的组合物和使用相同方法促进大肠癌转移的MAEC活性的分析方法

摘要

The present invention relates to a composition for analyzing the activity of mucosa-associatediEscherichia coli/i (MAEC) in macrophage inhibitory cytokine 1 (MIC-1) and a method for analyzing the activity of MAEC which promotes the metastasis of colorectal cancer using the same. Provided is a composition for analyzing the activity of MAEC which promotes the metastasis of colorectal cancer, wherein an antibody which specifically recognizes an MIC-1 protein is included as an active ingredient. Also, provided is a method for analyzing the activity of MAEC which promotes the metastasis of colorectal cancer, the method comprising the steps of: exposing samples suspected to promote the metastasis of colorectal cancer to colorectal cancer cells; collecting detached colorectal cancer cells from among the exposed colorectal cancer cells; measuring the expression level of an MIC-1 protein from the collected colorectal cancer cells; measuring the survival rate of the collected colorectal cancer cells; and comparing the expression level and colorectal cancer cell survival rate of the measured MIC-1 protein with those of a control group.;COPYRIGHT KIPO 2014
机译:本发明涉及用于分析巨噬细胞抑制性细胞因子1(MIC-1)中的粘膜相关性大肠杆菌(MAEC)的活性的组合物和分析用于促进转移的MAEC活性的方法。使用相同的结直肠癌。提供用于分析促进结直肠癌的转移的MAEC的活性的组合物,其中包括特异性识别MIC-1蛋白的抗体作为活性成分。另外,提供了一种分析MAEC促进结直肠癌转移的活性的方法,该方法包括以下步骤:将怀疑促进结直肠癌转移的样品暴露于结直肠癌细胞;从暴露的结直肠癌细胞中收集分离的结直肠癌细胞;测量收集的结直肠癌细胞中MIC-1蛋白的表达水平;测量收集的结直肠癌细胞的存活率;并比较测定的MIC-1蛋白与对照组的表达水平和结直肠癌细胞存活率。; COPYRIGHT KIPO 2014

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