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Increased acquired protease inhibitor drug resistance mutations in minor HIV-1 quasispecies from infected patients suspected of failing on national second-line therapy in South Africa

机译：增加了受感染患者在南非国家二线治疗失败的感染患者中患有次要HIV-1 Quaspecies中的蛋白酶抑制剂抗药性突变

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The online version contains supplementary material available at 10.1186/s12879-021-05905-2.

机译：在线版本包含10.1186 / S12879-021-05905-2可用的补充材料。

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期刊名称 BMC Infectious Diseases
作者
Adetayo Emmanuel Obasa; Anoop T. Ambikan; Soham Gupta; Ujjwal Neogi; Graeme Brendon Jacobs;
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作者单位

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年(卷),期 2021(-1),-1
年度 2021
页码 -1
总页数 8
原文格式 PDF
正文语种
中图分类病毒传染病;
关键词
High-throughput sequencing (HTS); Boosted protease inhibitors (bPIs); Non-nucleoside reverse transcriptase inhibitors (NNRTIs); Nucleoside reverse transcriptase inhibitors (NRTIs);

机译：高通量测序（HTS）;增强蛋白酶抑制剂（BPI）;非核苷逆转录酶抑制剂（NNRTIS）;核苷逆转录酶抑制剂（NRTIS）;

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专利

1. Increased acquired protease inhibitor drug resistance mutations in minor HIV-1 quasispecies from infected patients suspected of failing on national second-line therapy in South Africa [J] . Adetayo Emmanuel Obasa, Anoop T. Ambikan, Soham Gupta, BMC Infectious Diseases . 2021,第1期

机译：来自南非国家二线治疗失败的受感染患者的次要HIV-1 Quasispecies中获得的蛋白酶抑制剂抗药性突变增加
2. Protease Inhibitor Resistance Is Uncommon in HIV-1 Subtype C Infected Patients on Failing Second-Line Lopinavir/r-Containing Antiretroviral Therapy in South Africa [J] . Carole L.Wallis, John W.Mellors, Willem D. F.Venter, AIDS Research and Treatment . 2011,第4期

机译：在南非失败的二线洛吡那韦/ r含抗逆转录病毒疗法失败的HIV-1 C型感染的患者中，蛋白酶抑制剂的耐药性并不常见
3. Major drug resistance mutations to HIV-1 protease inhibitors (PI) among patients exposed to PI class failing antiretroviral therapy in S?o Paulo State, Brazil [J] . Giselle de Faria Romero Soldi, Isadora Coutinho Ribeiro, Cintia Mayumi Ahagon, PLoS One . 2019,第10期

机译：在S-O Paulo State，巴西（Paulo State）暴露于PI级失败的患者的主要耐药性突变（PI）。
4. Computational Mutation Scanning and Drug Resistance Mechanisms of HIV-1 Protease Inhibitors [C] . Ge-Fei Hao, Guang-Fu Yang, Chang-Guo Zhan ICMSI;International conference of molecular simulations and applied informatics technologies . 2010

机译：HIV-1蛋白酶抑制剂的计算突变扫描和耐药机制
5. Protease Inhibitor Resistance Is Uncommon in HIV-1 Subtype C Infected Patients on Failing Second-Line Lopinavir/r-Containing Antiretroviral Therapy in South Africa [O] . Carole L. Wallis, John W. Mellors, Willem D. F. Venter, 2011

机译：在南非失败的二线洛潘那韦/ r含抗逆转录病毒疗法失败的HIV-1 C型感染的患者中蛋白酶抑制剂的耐药性并不常见
6. Increased acquired protease inhibitor drug resistance mutations in minor HIV-1 quasispecies from infected patients suspected of failing on national second-line therapy in South Africa [O] . Adetayo Emmanuel Obasa, Anoop T Ambikan, Soham Gupta, 2021

机译：增加了受感染患者在南非国家二线治疗失败的感染患者中患有次要HIV-1 Quaspecies中的蛋白酶抑制剂抗药性突变

Increased acquired protease inhibitor drug resistance mutations in minor HIV-1 quasispecies from infected patients suspected of failing on national second-line therapy in South Africa

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