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Rare presentation of bilateral thumb psoriatic arthritis treated with arthrodesis: a case report

机译:稀有关节术治疗双侧拇指银屑病关节炎的罕见介绍:案例报告

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摘要

Psoriatic arthritis (PsA) is a seronegative inflammatory arthritis that occurs concomitantly with cutaneous manifestations and tendinous pathology that affects up to 1% of the general population. While the majority of cases are mild, nearly 20% of PsA patients will progress to severe disease manifesting as debilitating polyarticular inflammation and joint destruction. PsA is most commonly asymmetric and bilateral severe disease involving the same joints in each hand has rarely been reported in the literature. It is estimated that PsA only presents bilaterally in a quarter of patients. The recent increase in popularity and efficacy of disease-modifying anti-rheumatic drugs (DMARDs) has led to increasing rarity of such severe disease progression. We present a case of a 47-year-old male with PsA who had a unique pattern of bilateral first metacarpophalangeal (MP) and interphalangeal (IP) involvement with minimal erosion leading to significant joint pain, instability, dislocation, and loss of function. After failure of conservative treatment that included both DMARDs and non-steroidal anti-inflammatory drugs (NSAIDs), the patient opted for surgical management. The purpose of this report is to identify a rare presentation of PsA and consider the significance of MP joint arthrodesis as a viable treatment to restore functional status and improve quality of life.
机译:银屑病关节炎(PSA)是一种血清可炎症性关节炎,伴随着皮肤表现和腹股沟病理,影响高达1%的一般人群。虽然大多数病例均为轻度,但近20%的PSA患者将进入严重的疾病,表现为衰弱的多种炎症和联合破坏。 PSA是最常见的不对称性和双侧严重疾病,涉及每只手的相同关节很少在文献中报道。据估计,PSA仅在四分之一的患者中呈现。近期疾病改性抗风湿药物(DMARDs)的普及和疗效的增加导致了这种严重疾病进展的罕见。我们提出了一个47岁男性的案例,PSA具有独特的双侧第一次Metacarpophalangeal(MP)和差异(IP)涉及最小侵蚀,导致显着的关节疼痛,不稳定性,错位和功能丧失。经过保守治疗失败,包括DMARD和非甾体抗炎药(NSAIDs),患者选择手术管理。本报告的目的是鉴定PSA的罕见呈递,并考虑MP关节关节作为恢复功能状况和提高生活质量的可行疗法的重要性。

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