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Region-specific amyloid-β accumulation in the olfactory system influences olfactory sensory neuronal dysfunction in 5xFAD mice

机译：嗅觉系统中的区域特异性淀粉样蛋白-β积累会影响5xFAD小鼠中的嗅觉感官神经元功能障碍

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摘要

The online version contains supplementary material available at 10.1186/s13195-020-00730-2.

机译：在线版包含10.1186 / s13195-020-00730-2可用的补充材料。

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期刊名称 Alzheimers Research Therapy
作者
Gowoon Son; Seung-Jun Yoo; Shinwoo Kang; Ameer Rasheed; Da Hae Jung; Hyunjun Park; Bongki Cho; Harry W. M. Steinbusch; Keun-A Chang; Yoo-Hun Suh; Cheil Moon;
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年(卷),期 2021(-1),-1
年度 2021
页码 -1
总页数 20
原文格式 PDF
正文语种
中图分类精神病学;
关键词
Alzheimer’s disease; Olfactory dysfunction; β-amyloid; 5xFAD; Olfactory sensory neuron; Zonal organization; Odor detection test; Ca;

机译：阿尔茨海默病;嗅觉功能障碍;β-淀粉样蛋白;5xFAD;嗅觉感觉神经元;区间组织;气味检测试验;CA;
入库时间 2022-08-21 11:54:38

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专利

1. Region-specific amyloid-β accumulation in the olfactory system influences olfactory sensory neuronal dysfunction in 5xFAD mice [J] . Gowoon Son, Seung-Jun Yoo, Shinwoo Kang, Alzheimer s Research & Therapy . 2021,第1期

机译：嗅觉系统中的区域特异性淀粉样蛋白-β积累影响5xFAD小鼠中的嗅觉感官神经元功能障碍
2. SB203580, a p38MAPK inhibitor, attenuates olfactory dysfunction by inhibiting OSN apoptosis in AR mice (activation and involvement of the p38 mitogen‐activated protein kinase in olfactory sensory neuronal apoptosis of OVA‐induced allergic rhinitis) [J] . Xian Gao, Na Li, Jisheng Zhang Brain and Behavior . 2019,第6期

机译：SB203580，一种p38MAPK抑制剂，通过抑制AR小鼠的OSN凋亡来减轻嗅觉功能障碍（p38丝裂原活化蛋白激酶的激活和参与OVA致敏性鼻炎的嗅觉神经元凋亡）
3. The terminal nerve plays a prominent role in GnRH-1 neuronal migration independent from proper olfactory and vomeronasal connections to the olfactory bulbs The terminal nerve plays a prominent role in GnRH-1 neuronal migration independent from proper olfactory and vomeronasal connections to the olfactory bulbs The terminal nerve plays a prominent role in GnRH-1 neuronal migration independent from proper olfactory and vomeronasal connections to the olfactory bulbs [J] . Aparna Prasad, Paolo E. Forni, Jennifer M. Lin, Biology Open . 2017,第10期

机译：终末神经在GnRH-1神经元迁移中起着重要作用，而与嗅球的正确嗅觉和犁鼻连接无关。神经在GnRH-1神经元迁移中起着重要作用，而与嗅球的正确嗅觉和犁鼻连接无关
4. Studies on the Correlation with Olfactory Dysfunction in a Transgenic Mice Model of Alzheimer's Disease [C] . Ameer Rasheed, Ji Hye Lee, Yoo Hun Suh, Conference on nano-bio sensing, imaging, and spectroscopy . 2013

机译：阿尔茨海默氏病转基因小鼠模型与嗅觉功能障碍的相关性研究
5. Olfactory marker protein is critical for functional maturation of olfactory sensory neurons in mice. [D] . Lee, Anderson Chun Yi. 2009

机译：嗅觉标记蛋白对于小鼠嗅觉感觉神经元的功能成熟至关重要。
6. SB203580 a p38MAPK inhibitor attenuates olfactory dysfunction by inhibiting OSN apoptosis in AR mice (activation and involvement of the p38 mitogen‐activated protein kinase in olfactory sensory neuronal apoptosis of OVA‐induced allergic rhinitis) [O] . Xian Gao, Na Li, Jisheng Zhang 2019

机译：SB203580一种p38MAPK抑制剂通过抑制AR小鼠的OSN凋亡来减轻嗅觉功能障碍（p38丝裂原活化蛋白激酶的激活和参与OVA诱导的变应性鼻炎的嗅觉神经元凋亡）
7. Region-specific amyloid-β accumulation in the olfactory system influences olfactory sensory neuronal dysfunction in 5xFAD mice [O] . Gowoon Son, Seung-Jun Yoo, Shinwoo Kang, 2021

机译：嗅觉系统中的区域特异性淀粉样蛋白-β积累会影响5xFAD小鼠中的嗅觉感官神经元功能障碍
8. Odor-Evoked Inhibition of Olfactory Sensory Neurons Drives Olfactory Perception in Drosophila. [R] . Zeng, X., Cao, L., Yang, D., 2017

机译：气味诱发抑制嗅觉感觉神经元驱动果蝇的嗅觉感知。

Region-specific amyloid-β accumulation in the olfactory system influences olfactory sensory neuronal dysfunction in 5xFAD mice

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