Anti-Biofilm Activities of Manuka Honey against Escherichiacoli O157:H7

摘要

Manuka honey (MH) has been shown anti-bacterial activity against severalpathogenic bacteria. However, the inhibitory effect of MH on biofilm formationby O157:H7 has not yet been examined. In thisstudy, MH significantly reduced O157:H7 biofilm.Moreover, pre- and post-treatment with MH also significantly reduced O157:H7 biofilm. Cellular metabolic activities exhibited thatthe viability of O157:H7 biofilm cells was reduced inthe presence of MH. Further, colony forming unit of MH-treated O157:H7 biofilm was significantly reduced by over 70%.Collectively, this study suggests the potential of anti-biofilm properties of MHwhich could be applied to control O157:H7.