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Nonalcoholic fatty liver disease in type 2 diabetes: awareness is the first step toward change

机译:2型糖尿病中的非酒精性脂肪肝病:意识是变革的第一步

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摘要

In a recent article published in , Younossi . provided a comprehensive systematic review and meta-analysis on the prevalence of NAFLD, NASH and advanced fibrosis in patients with type 2 diabetes mellitus (T2DM) across the globe ( ). Among the 80 studies included in the final analysis (for a total of 49,419 patients) the prevalence of NAFLD was between 50–70% in all continents, except for Africa, where a prevalence of 30.4% was reported. This lower prevalence of NAFLD in Africa is consistent with prior reports showing a lower prevalence of NAFLD among African-American individuals ( , ). Of note, once African-American patients develop NAFLD, their progression to NASH and advanced fibrosis is similar to other ethnic groups, and still a significant cause of cirrhosis in this population ( ).
机译:在最近发表于Younossi的文章中。为全球2型糖尿病(T2DM)患者NAFLD,NASH和先进纤维化患病率进行了综合系统审查和荟萃分析。在最终分析中包含的80项研究中(总共4​​9,419名患者),所有大陆的NAFLD的患病率在50-70%之间,除非非洲,报告了30.4%的患病率。非洲NAFLD的这种较低的患病率与现有的报告一致,显示非洲裔美国人(,)中NAFLD患病率较低。值得注意的是,一旦非裔美国人患者发展NAFLD,他们对纳什和先进纤维化的进展类似于其他族群,并且仍然是这种人群()肝硬化的重要原因。

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