Identification of Fungal Species and Detection of Azole-Resistance Mutations in the Aspergillus fumigatuscyp51A Gene at a South Korean Hospital

摘要

With changing fungal epidemiology and azole resistance in species, identifying fungal species and susceptibility patterns is crucial to the management of aspergillosis and mucormycosis. The objectives of this study were to evaluate performance of panfungal polymerase chain reaction (PCR) assays on formalin-fixed paraffin embedded (FFPE) samples in the identification of fungal species and in the detection of azole-resistance mutations in the gene at a South Korean hospital.