Initial Evidence for Brain Plasticity Following a Digital TherapeuticIntervention for Depression

摘要

Digital therapeutics such as cognitive–emotional training have begun to showpromise for the treatment of major depressive disorder. Available clinicaltrial data suggest that monotherapy with cognitive–emotional training usingthe Emotional Faces Memory Task is beneficial in reducing depressivesymptoms in patients with major depressive disorder. The aim of this studywas to investigate whether Emotional Faces Memory Task training for majordepressive disorder is associated with changes in brain connectivity andwhether changes in connectivity parameters are related to symptomaticimprovement.