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Risk ranking of chemical and microbiological hazards in food

机译:食品中化学和微生物危害的风险等级

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摘要

Risk ranking is a versatile tool used to prioritise activities performed by public health regulatory bodies. It also allows efficient communication between all stakeholders in the process of risk analysis. However, risk ranking methods are still not optimal. Because of the different approaches employed in the risk assessment of microbiological agents and chemicals, it is difficult to rank them together using the same metrics. In our work, we first discuss differences and commonalities between chemical and microbiological risk assessment to provide a starting point for consideration of a common risk ranking platform. In the second part, we perform risk ranking of contaminants and regulated chemicals using the recently developed Risk Thermometer tool. In this approach, chemicals are not ranked solely on the basis of the margin of exposure between a reference value and the exposure, but also by considering the severity of the critical health effects used. The results show that ranking using both methods provides different results from the use of either method alone. Overall, specific chemical groups (i.e. heavy metals, pesticides, etc.) do not generally rank higher or lower, but individual compounds are scattered in the rankings from low to high. Risk ranking methods demand further development to gain wide acceptability and recognition.
机译:风险分级是一种通用工具,可用于对公共卫生监管机构执行的活动进行优先级排序。它还允许在风险分析过程中所有利益相关者之间进行有效的沟通。但是,风险分级方法仍然不是最佳方法。由于在微生物制剂和化学药品的风险评估中采用了不同的方法,因此很难使用相同的指标对它们进行排序。在我们的工作中,我们首先讨论化学和微生物风险评估之间的差异和共性,以为考虑通用风险排名平台提供一个起点。在第二部分中,我们使用最新开发的风险温度计工具对污染物和受管制化学品进行风险排名。在这种方法中,不仅仅根据参考值与暴露之间的暴露裕度对化学药品进行排名,还应考虑所使用的严重健康影响的严重性。结果表明,使用这两种方法进行排名与单独使用这两种方法提供的结果不同。总体而言,特定的化学基团(即重金属,农药等)通常不会排名较高或较低,但是各个化合物的排名从低到高排列。风险分级方法需要进一步发展以获得广泛的接受和认可。

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