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Chronic peritoneal dialysis in children: a single-centre experience in Jordan

机译:儿童慢性腹膜透析:约旦的单中心经验

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摘要

The aim of the present study is to share the experience of chronic peritoneal dialysis (PD) at King Hussein Medical Center, Amman, Jordan, and to highlight the complications of this procedure. This is a retrospective chart review study for all the children from day 1 of life to 14 years, who underwent chronic PD for end-stage renal disease (ESRD) during the period of 10 years extending from 2009 to 2019. The following data were collected: mode of dialysis, type of peritoneal dialysis, age of starting peritoneal dialysis, gender, aetiology of ESRD, duration on PD, complications and outcome. A total number of 269 children were included: 229 patients received haemodialysis and 40 children (22 boys and 18 girls) received PD. Of those, two children were on automated PD and 38 children were on continuous ambulatory peritoneal dialysis. The mean age at the start of PD was 62 ± 38 months. The mean duration of PD was 43 months. The mean catheter duration was 34 months. Six patients were shifted to haemodialysis permanently and four patients received a kidney transplant. Eleven patients died. The most common complications were peritonitis (52.5%), exit-site infection (30%) and malfunctioning catheter (12.5%). The rate of peritonitis was one episode per 22 patient-months. Peritoneal dialysis is a promising mode of dialysis for children in Jordan. Peritonitis is the most common complication associated with PD. Kidney transplantation is the best modality of renal replacement therapy in terms of long-term survival and quality of life and should be encouraged on national level.
机译:本研究的目的是分享约旦安曼国王侯赛因医学中心的慢性腹膜透析(PD)经验,并强调该手术的并发症。这是一项回顾性图表审查研究,针对从生命的第一天到14岁的所有儿童,这些儿童在2009年至2019年的10年期间接受了终末期肾病(ESRD)的慢性PD治疗。收集了以下数据:透析方式,腹膜透析类型,开始腹膜透析的年龄,性别,ESRD的病因,PD持续时间,并发症和预后。总共包括269名儿童:229名接受血液透析的患者和40名儿童(22名男孩和18名女孩)接受了PD。其中,有2名儿童接受自动PD治疗,有38名儿童正在进行非卧床腹膜透析。 PD开始时的平均年龄为62±38个月。 PD的平均持续时间为43个月。平均导管持续时间为34个月。六名患者永久转移到血液透析,四名患者接受了肾脏移植。 11例患者死亡。最常见的并发症是腹膜炎(52.5%),出口部位感染(30%)和导管故障(12.5%)。腹膜炎的发生率为每22个患者月1次发作。腹膜透析是约旦儿童透析的一种有希望的方式。腹膜炎是与PD相关的最常见并发症。就长期生存和生活质量而言,肾脏移植是肾脏替代疗法的最佳方式,应在国家一级予以鼓励。

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