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Self-Organization of the Biological Evolution

机译:生物进化的自组织

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摘要

We report here experiments carried out with nonpathogenic bacterial strains and their phages. This research yielded interesting insights into their activities, occasionally producing genetic variants of different types. In order to not interfere with the genetic stability of the parental strains involved, we found that the bacteria are genetically equipped to only rarely produce a genetic variant, which may occur by a number of different approaches. On the one hand, the genes of relevance for the production of specific genetic variants are relatively rarely expressed. On the other hand, other gene products act as moderators of the frequencies that produce genetic variants. We call the genes producing genetic variants and those moderating the frequencies of genetic variation “evolution genes”. Their products are generally not required for daily bacterial life. We can, therefore, conclude that the bacterial genome has a duality. Some of the bacterial enzymes involved in biological evolution have become useful tools (e.g., restriction endonucleases) for molecular genetic research involving the genetic set-up of any living organism.
机译:我们在这里报告对非致病性细菌菌株及其噬菌体进行的实验。这项研究对它们的活动产生了有趣的见解,偶尔会产生不同类型的遗传变异。为了不干扰所涉及的亲本菌株的遗传稳定性,我们发现该细菌具有遗传装备,仅极少产生遗传变异,这可以通过许多不同的方法发生。一方面,与特定遗传变异产生有关的基因相对很少被表达。另一方面,其他基因产物充当产生遗传变异的频率的调节剂。我们称产生遗传变异的基因和调节遗传变异频率的基因称为“进化基因”。他们的产品通常不需要日常细菌生活。因此,我们可以得出结论,细菌基因组具有双重性。涉及生物进化的某些细菌酶已成为用于涉及任何活生物体遗传结构的分子遗传研究的有用工具(例如限制性核酸内切酶)。

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