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Circadian‐timed quick‐release bromocriptine lowers elevated resting heart rate in patients with type 2 diabetes mellitus

机译：昼夜节律的速释溴隐亭可降低2型糖尿病患者的静息心率

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摘要

Sympathetic nervous system (SNS) overactivity is a risk factor for insulin resistance and cardiovascular disease (CVD). We evaluated the impact of bromocriptine‐QR, a dopamine‐agonist antidiabetes medication, on elevated resting heart rate (RHR) (a marker of SNS overactivity in metabolic syndrome), blood pressure (BP) and the relationship between bromocriptine‐QR's effects on RHR and HbA1c in type 2 diabetes subjects.

机译：交感神经系统（SNS）过度活跃是胰岛素抵抗和心血管疾病（CVD）的危险因素。我们评估了多巴胺激动剂多巴胺激动剂溴隐亭-QR对静息心率（RHR）（代谢综合征中SNS过度活跃的标志），血压（BP）的影响以及溴隐亭-QR对RHR的影响之间的关系2型糖尿病患者中的HbA1c和HbA1c。

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期刊名称 Endocrinology Diabetes Metabolism
作者
Bindu Chamarthi; Aaron Vinik; Michael Ezrokhi; Anthony H. Cincotta;
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作者单位

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年(卷),期 2020(3),1
年度 2020
页码 -1
总页数 13
原文格式 PDF
正文语种
中图分类基础医学;
关键词
dopamine; sympathetic nervous system; type 2 diabetes;

机译：多巴胺;交感神经系统;2型糖尿病;

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专利

1. Circadian‐timed quick‐release bromocriptine lowers elevated resting heart rate in patients with type 2 diabetes mellitus [J] . Bindu Chamarthi, Aaron Vinik, Michael Ezrokhi, Endocrinology, Diabetes & Metabolism . 2020,第1期

机译：昼夜定期快速释放溴杉裂降低了2型糖尿病患者的休息心率升高
2. Efficacy and safety of bromocriptine quick release as an add on therapy with metformin and glipizide in type 2 diabetes mellitus patients: an open label randomized controlled study [J] . Nithyapriya M., S. Purushotaman International Journal of Basic & Clinical Pharmacology . 2019,第4期

机译：溴隐亭快速释放作为二甲双胍和格列吡嗪治疗2型糖尿病患者的疗效和安全性：一项开放标签的随机对照研究
3. Risk of elevated resting heart rate on the development of type 2 diabetes in patients with clinically manifest vascular diseases [J] . Remy H H Bemelmans, Annemarie M J Wassink, Yolanda van der Graaf, European journal of endocrinology . 2012,第4期

机译：临床表现为血管疾病的患者中静息心率升高对2型糖尿病发展的风险
4. Heart rate complexity and cardiac sympathetic dysinnervation in patients with type 2 diabetes mellitus [C] . Baumert, Mathias, Sacre, Julian W Annual Conference of Japanese Society for Medical and Biological Engineering;Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2013

机译：2型糖尿病患者的心律复杂性和心脏交感神经营养不良
5. Disruption of circadian rhythm impairs pancreatic islet function and increases susceptibility to beta-cell failure, while pathological complications of Type 2 Diabetes Mellitus have scant effects on the circadian system [D] . Qian, Jingyi 2015

机译：昼夜节律的破坏损害胰岛胰岛功能，并增加对β细胞衰竭的敏感性，而2型糖尿病的病理并发症对昼夜节律体系具有很少的影响
6. Resting Heart Rate and the Risk of Microvascular Complications in Patients With Type 2 Diabetes Mellitus [O] . Graham S. Hillis, Jun Hata, Mark Woodward, 2012

机译：2型糖尿病患者的静息心率和微血管并发症风险
7. Circadian‐timed quick‐release bromocriptine lowers elevated resting heart rate in patients with type 2 diabetes mellitus [O] . Bindu Chamarthi, Aaron Vinik, Michael Ezrokhi, 2019

机译：昼夜定期快速释放溴杉裂降低了2型糖尿病患者的休息心率升高

Circadian‐timed quick‐release bromocriptine lowers elevated resting heart rate in patients with type 2 diabetes mellitus

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