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Targeted alpha therapy with astatine-211-labeled anti-PSCA A11 minibody shows antitumor efficacy in prostate cancer xenografts and bone microtumors

机译：带有a素211标记的抗PSCA A11微型抗体的靶向α疗法在前列腺癌异种移植物和骨微瘤中显示出抗肿瘤功效

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摘要

Biodistribution with At-A11 minibody

机译：At-A11微型抗体的生物分布

著录项

期刊名称 EJNMMI Research
作者
Tom A. Bäck; Karin Jennbacken; Malin Hagberg Thulin; Sture Lindegren; Holger Jensen; Tove Olafsen; Paul J. Yazaki; Stig Palm; Per Albertsson; Jan-Erik Damber; Anna M. Wu; Karin Welén;
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年(卷),期 2020(10),-1
年度 2020
页码 -1
总页数 12
原文格式 PDF
正文语种
中图分类
关键词
Metastatic prostate cancer; Targeted alpha therapy; Alpha particles; Alpha-radioimmunotherapy; Astatine-211; Prostate stem cell antigen; Intratibial microtumors;

机译：转移性前列腺癌;靶向α治疗;α颗粒;α放射免疫治疗;A 211;前列腺干细胞抗原;胫骨内微肿瘤;

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专利

1. Targeted alpha therapy with astatine-211-labeled anti-PSCA A11 minibody shows antitumor efficacy in prostate cancer xenografts and bone microtumors [J] . Tom A. B?ck, Karin Jennbacken, Malin Hagberg Thulin, EJNMMI Research . 2020,第Suppla1期

机译：靶向α疗法astatine-211标记的抗psca a11小纤维显示出前列腺癌异种移植物和骨髓癌的抗肿瘤效果
2. Quantitative immunoPET of prostate cancer xenografts with 89Zr- and 124I-labeled anti-PSCA A11 minibody. [J] . Scott M Knowles, Kirstin A Zettlitz, Richard Tavaré, The Journal of Nuclear Medicine . 2014,第3期

机译：用89Zr和124I标记的抗PSCA A11微型抗体对前列腺癌异种移植物进行定量免疫PET。
3. Quantitative ImmunoPET of Prostate Cancer Xenografts with 89Zr- and 124I-Labeled Anti-PSCA A11 Minibody [J] . Scott M. Knowles, Kirstin A. Zettlitz, Richard Tavar??, The Journal of Nuclear Medicine . 2014,第3期

机译：带有89Zr和124I标签的抗PSCA A11微型抗体的前列腺癌异种移植物的定量ImmunoPET
4. Therapeutic efficacy of radioactive nanoparticles ~(103)Pd:PdAu-PEG NPs in a PC3 prostate cancer xenograft model [C] . Myriam Laprise-Pelletier, Jean Lagueux, Marie-France Cote, World biomaterials congress . 2016

机译：放射性纳米粒子〜（103）Pd：PdAu-PEG NPs在PC3前列腺癌异种移植模型中的治疗效果
5. Integrating genomics and molecular biology: identifying transcriptional targets for the prostate cancer oncogene SOX4 and evaluating the efficacy of Aurora kinase inhibition in chemotherapy-resistant ovarian cancer [D] . Scharer, Christopher D. 2009

机译：整合基因组学和分子生物学：鉴定前列腺癌致癌基因SOX4的转录靶标并评估Aurora激酶抑制作用对化疗耐药的卵巢癌的疗效
6. Quantitative ImmunoPET of Prostate Cancer Xenografts with 89Zr- and 124I-Labeled Anti-PSCA A11 Minibody [O] . Scott M. Knowles, Kirstin A. Zettlitz, Richard Tavaré, -1

机译：带有89Zr和124I标签的抗PSCA A11微型抗体的前列腺癌异种移植物的定量ImmunoPET
7. Engineering A11 Minibody-Conjugated, Polypeptide-Based Gold Nanoshells for Prostate Stem Cell Antigen (PSCA)–Targeted Photothermal Therapy [O] . Kristine M. Mayle, Kathryn R. Dern, Vincent K. Wong, 2016

机译：工程A11用于前列腺干细胞抗原（PSCA）前列腺干细胞抗原（PSCA）的基于多肽的金纳米乳液

Targeted alpha therapy with astatine-211-labeled anti-PSCA A11 minibody shows antitumor efficacy in prostate cancer xenografts and bone microtumors

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