The Burden of Frailty on Mood Cognition Quality of Life and Level of Independence in Patients on Hemodialysis: Regina Hemodialysis Frailty Study

摘要

The prevalence of frailty is disproportionately increased in patients with chronic kidney disease (CKD) in comparison with non-CKD counterparts and is the highest in patients on hemodialysis (HD). While the cross-sectional measurement of frailty on HD has been associated with adverse clinical events, there is a paucity of data on longitudinal assessment of frailty and its relationship to outcomes.